Negative celiac blood work when on a gluten-free diet

Katarina Mollo MEd, RDN, LDN
Q: If you have been gluten-free for 6 years after being diagnosed with celiac disease, can your blood work come back negative?

Answer


Yes, if you are on a gluten-free diet you ideally would want your blood work to come back at negative levels. Elevated antibodies indicate ongoing damage in the intestine; the most common cause of elevated levels is continued gluten exposure. Having undetectable levels indicate that the gluten-free diet is working well. Since you have been gluten-free for six years, it is not unusual to have undetectable levels of celiac-related antibodies. Note that having a negative blood result with a previously established diagnosis of celiac disease does not mean your celiac disease has resolved, but that it is well-controlled. 

Note: This information is provided by NCA and Katarina Mollo MEd, RDN, LDN, NCA's Director of Education. This information is meant for educational purposes only and is not intended to substitute for personalized medical advice or replace any medical advice provided directly to you by your health care provider. No liability is assumed by the NCA or Katarina Mollo, MEd, RDN, LDN by providing this information.

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